Description:

?
IdeZProtease(IgG-specific)isarecombinantantibodyspecificproteaseclonedfromStreptococcusequisubspecieszooepidemicusthatrecognizesallhuman,sheep,monkey,andrabbitIgGsubclasses,specificallycleavingatasinglerecognitionsitebelowthehingeregion,yieldingahomogenouspoolofF(ab′)2andFcfragments.IdeZProteasemoreeffectivelycleavesmurineIgG2athanIdeS.
 DigestionoflgGwithIdeZProtease(lgG-specific),followedbydenaturation.
DigestionoflgGwithIdeZProtease(lgG-specific),followedbydenaturation.
ProductSource
ClonedfromStreptococcusequisubspecieszooepidemicusandexpressedinE.coli.?ReagentsSupplied
Thefollowingreagentsaresuppliedwiththisproduct:
|  | Storeat(°C) | Concentration | 
| GlycoBuffer2 | -20 | 10X | 
Notes:
Storeat-20°Cforuptotwoyears.IdeZProteaseefficientlycleaveshuman,humanized,chimeric,sheep,rabbitandmonkeyIgGaswellasmouseIgG2aandIgG3.IdeZProteasewillalsocleaveFc-fusionproteins,suchasEnbrel.IdeZProteasedoesnotcleavemouseIgG1orIgG2b,rat,porcine,bovineorgoatIgG.Italsodoesnotcleavenon-IgGisotypesincludingIgA,IgM,IgDandIgE.