| Immunogen | RecombinantratGAP-43(completesequence). | 
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. | 
| Host | Rabbit | 
| Specificity | RecognizesGrowthAssociatedProtein-43(GAP-43). | 
| SpeciesReactivity | - Human
 - Mouse
 - Rat
 - Chicken
 - Bovine
 
  | 
| SpeciesReactivityNote | Reactstoahighdegreewithmouse.Reactstoalesserdegreewithrat,human,bovineandchicken.Otherspecieshavenotbeentested. | 
| AntibodyType | PolyclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Theproteinencodedbythisgenehasbeentermeda"growth"or"plasticity"proteinbecauseitisexpressedathighlevelsinneuronalgrowthconesduringdevelopmentandaxonalregeneration.Thisencodedproteinisconsideredacrucialcomponentofaneffectiveregenerativeresponseinthenervoussystem. | 
| GeneSymbol |  | 
| PurificationMethod | AmmoniumSulfatePrecipitation | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P17677#Thisproteinisassociatedwithnervegrowth.Itisamajorcomponentofthemotilegrowthconesthatformthetipsofelongatingaxons. SIZE:238aminoacids;24803Da SUBUNIT:BindscalmodulinwithagreateraffinityintheabsenceofCa(2+)thaninitspresence(Bysimilarity). SUBCELLULARLOCATION:Cellmembrane;Peripheralmembraneprotein;Cytoplasmicside.Cellprojection,growthconemembrane;Peripheralmembraneprotein;Cytoplasmicside.Celljunction,synapse.Note=Cytoplasmicsurfaceofgrowthconeandsynapticplasmamembranes. PTM:PhosphorylationofthisproteinbyaproteinkinaseCisspecificallycorrelatedwithcertainformsofsynapticplasticity. SIMILARITY:SwissProt:P17677##Belongstotheneuromodulinfamily.&Contains1IQdomain. | 
| MolecularWeight | 23.6kDa |